HRID1612369

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COC(=O)c1nc(N[C@@H]2c3ccccc3C[C@@H]2O)cnc1Br

HCID58583440

未命名化合物

结构：COc1cncc(N[C@]2(C)c3ccccc3C[C@@H]2O)n1

HCID69664630

未命名化合物

PRODUCTS

生成物

结构：COc1nc(N[C@@H]2c3ccccc3C[C@@H]2O)cnc1Br

HCID58631232

未命名化合物

PROCEDURE

实验过程

Following the procedure for the preparation of methyl 3-bromo-6-{[(1R,2S)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino}pyrazine-2-carboxylate but substituting methyl (1R,2S)-1-[(6-methoxypyrazin-2-yl)amino]-2,3-dihydro-1H-inden-2-ol and making non-critical variations provided the title compound as a solid: 1H NMR (CDCl3) δ 2.07, 3.03-3.07, 3.25-3.30, 3.98, 4.76, 5.38, 7.26-7.32, 7.45; MS (ESI+) for C14H14BrN3O2 m/z 336 (M+H)+.