HRID1612371

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COC(=O)c1nc(N[C@@H]2c3ccccc3C[C@@H]2O)cnc1Br

HCID58583440

未命名化合物

结构：COc1nc(N[C@@H]2c3ccccc3C[C@@H]2O)cnc1-c1ccc(Cl)cc1Cl

HCID58631240

未命名化合物

PRODUCTS

生成物

结构：COc1nc(N[C@@H]2c3ccccc3C[C@@H]2O)c(Br)nc1-c1ccc(Cl)cc1Cl

HCID58631236

未命名化合物

PROCEDURE

实验过程

Following the procedure for the preparation of methyl 3-bromo-6-{[(1R,2S)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]amino}pyrazine-2-carboxylate but substituting (1R,2S)-1-{[5-(2,4-dichlorophenyl)-6-methoxypyrazin-2-yl]amino}-2,3-dihydro-1H-inden-2-ol and making non-critical variations provided the title compound as a solid: 1H NMR (CDCl3) δ 3.09-3.13, 3.29-3.34, 3.92, 4.81, 5.60-5.63, 5.99, 7.33-7.42, 7.49; MS (ESI+) for C20H16BrCl2N3O2 m/z 479 (M+H)+.