HRID1612373

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCc1nc(-c2ccc(Cl)cc2Cl)c(CC)nc1N[C@H]1c2ccccc2C[C@@H]1OC

HCID10127398

未命名化合物

结构：C=Cc1nc(-c2ccc(Cl)cc2Cl)c(OC)nc1N[C@@H]1c2ccccc2C[C@@H]1O

HCID58631243

未命名化合物

PRODUCTS

生成物

结构：C=Cc1nc(-c2ccc(Cl)cc2Cl)c(OC)nc1N[C@@H]1c2ccccc2C[C@@H]1OCC

HCID58631235

未命名化合物

PROCEDURE

实验过程

Following the procedure for the preparation of 5-(2,4-dichlorophenyl)-3,6-diethyl-N-[(1S,2S)-2-methoxy-2,3-dihydro-1H-inden-1-yl]pyrazin-2-amine but substituting (1R,2S)-1-{[5-(2,4-dichlorophenyl)-6-methoxy-3-vinylpyrazin-2-yl]amino}-2,3-dihydro-1H-inden-2-ol and making non-critical variations provided the title compound as a solid: 1H NMR (CDCl3) δ 1.11-1.14, 3.04-3.08, 3.37-3.44, 3.60-3.68, 3.84, 4.28-4.30, 5.34-5.37, 5.68-5.71, 5.90-5.99, 6.66-6.73, 7.14-7.26, 7.32-7.40; MS (ESI+) for C24H23Cl2N3O2 m/z 456 (M+H)+.