HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl [(7-{[2-(3-chlorophenyl)-2-hydroxyethyl]amino}-5,6,7,8-tetrahydronaphthalen-2-yl)oxy]acetate--hydrogen chloride (1/1) → SR-58611
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl [(7-{[2-(3-chlorophenyl)-2-hydroxyethyl]amino}-5,6,7,8-tetrahydronaphthalen-2-yl)oxy]acetate--hydrogen chloride (1/1) | HCID 121888 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | SR-58611 | HCID 3035442 | — |
Reaction Steps
Polymorphic SR58611 hydrochloride (4.46 g) is suspended at ambient temperature in 0.3 liter of propan-2-ol. After maintaining for 70 h under isothermal conditions, the suspension is composed of SR58611A hydrochloride, B form, >96%. IR spectrum and X-ray diffraction are in agreement.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06992211B2 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-509c01c0c76345a1a47bed4217f9a0ae |
| Source note | uspto-grants-2006_01 |