HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → ethyl (2R)-2-amino-3-phenylpropanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | D-Phenylalanine | HCID 71567 | — |
| Product | ethyl (2R)-2-amino-3-phenylpropanoate | HCID 721861 | 81% |
Reaction Steps
D-Phenylalanine (250 mg, 1.52 mmol) was dissolved in 5 ml EtOH previously bubbled in HCl (gas). The solution was brought to 100° C. and allowed to reflux overnight. The solvent was evaporated off affording 280 mg crude product. Recrystallization from EtOH/EtOAc/pentane gave 239 mg (81% yield) of D-phenylalanine ethyl ester as white crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06992207B2 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-81a151e82ee74a4a8054a3950ed94f7e |
| Source note | uspto-grants-2006_01 |