3,5-bis(2-oxopyrrolidin-1-yl)benzoic Acid → 3-Cyclobutyloxy-5-(2-oxopyrrolidin-1-yl)benzoic acid

HRID 1612457Notes

Reaction equation

HRID 1612457 reaction equation
O=C1CCCN1C1C=C(C=C(N2CCCC2=O)C=1)C(O)=O.[CH:22]1([O:26][C:27]2[CH:28]=[C:29]([CH:34]=[C:35]([N:37]3[CH2:41][CH2:40][CH2:39][C:38]3=[O:42])[CH:36]=2)[C:30]([O:32]C)=[O:31])[CH2:25][CH2:24][CH2:23]1>>[CH:22]1([O:26][C:27]2[CH:28]=[C:29]([CH:34]=[C:35]([N:37]3[CH2:41][CH2:40][CH2:39][C:38]3=[O:42])[CH:36]=2)[C:30]([OH:32])=[O:31])[CH2:25][CH2:24][CH2:23]1

Participants

3

Reactant 2

HCID 111620233,5-bis(2-oxopyrrolidin-1-yl)benzoic AcidHCID 22252979Methyl 3-cyclobutyloxy-5-(2-oxopyrrolidin-1-yl)benzoate

Product 1

HCID 222529923-Cyclobutyloxy-5-(2-oxopyrrolidin-1-yl)benzoic acid

Procedure

Prepared in an analogous manner to D8 from methyl 3-cyclobutyloxy-5-(2-oxopyrrolidin-1-yl)benzoate (D43).

Sources & evidence

ORD record
ord-6e48320c479d405d815ce3a81602fee9
Source dataset
uspto-grants-2006_01
Patent number
US06992103B2

Reaction notes

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