HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Isopropoxy-5-(2-oxopyrrolidin-1-yl)benzoic Acid → 3-Isopropoxy-N-[(S)-1-((2S,4R)-4-methyl-5-oxotetrahydrofuran-2-yl)-2-phenylethyl]-5-(2-oxopyrrolidin-1-yl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Isopropoxy-5-(2-oxopyrrolidin-1-yl)benzoic Acid | HCID 22253045 | — |
| Reactant | (3R,5S)-5-((S)-1-Amino-2-phenylethyl)-3-methyldihydrofuran-2-one | HCID 68679802 | — |
| Reactant | N-[(1S,2S,4R)-1-Benzyl-4-(3,3-dimethylbutylcarbamoyl)-2-hydroxypentyl]-3-bromo-4-fluorobenzamide | HCID 69589710 | — |
| Product | 3-Isopropoxy-N-[(S)-1-((2S,4R)-4-methyl-5-oxotetrahydrofuran-2-yl)-2-phenylethyl]-5-(2-oxopyrrolidin-1-yl)benzamide | HCID 69589765 | — |
Reaction Steps
Prepared in an analogous manner to D3 from 3-isopropoxy-5-(2-oxopyrrolidin-1-yl)benzoic acid (D16) and (3R,5S)-5-((S)-1-amino-2-phenylethyl)-3-methyldihydrofuran-2-one (D48).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06992103B2 |
| Source dataset | uspto-grants-2006_01 |
| ORD ID | ord-5433d746f5844f8f855845b670dc46e0 |
| Source note | uspto-grants-2006_01 |