反应详情

t-Butyl 2-benzylamino-6-methoxypyridine-4-carboxylate (D54) (0.294 g) in glacial AcOH (50 mL) was hydrogenated for 5 h at atmospheric pressure and room temperature in the presence of Pd—C (10%; 0.25 g). The catalyst was filtered off and washed thoroughly on the filter with MeOH. The combined filtrates were evaporated to give the title compound (D55) as a gum (0.184 g).

1. filtrationThe catalyst was filtered off
2. washwashed thoroughly on the
3. filtrationfilter with MeOH
4. customThe combined filtrates were evaporated