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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1612504Generated: November 1, 2026

N-[(1S,2S,4R)-1-Benzyl-4-(3,3-dimethylbutylcarbamoyl)-2-hydroxypentyl]-3-(2-oxopyrrolidin-1-yl)-5-phenylbenzamide → HCID 58583651, compound

https://huagongshe.com/reaction/1612504

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-[(1S,2S,4R)-1-Benzyl-4-(3,3-dimethylbutylcarbamoyl)-2-hydroxypentyl]-3-(2-oxopyrrolidin-1-yl)-5-phenylbenzamideHCID 10129098—
ReactantHCID 22252997HCID 22252997—
Reactant(2R,4S,5S)-5-Amino-4-hydroxy-2-methyl-6-phenylhexanoic acid (bicyclo[2.2.1]hept-2-yl)amideHCID 68889549—
ProductHCID 58583651HCID 58583651—

Reaction Steps

Prepared in an analogous manner to E6, from N-methyl-5-(2-oxo-pyrrolidin-1-yl)-N-propyl-isophthalamic acid (D65) and (2R,4S,5S)-5-amino-4-hydroxy-2-methyl-6-phenylhexanoic acid (bicyclo[2.2.1]hept-2-yl)amide (D29).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06992103B2
Source datasetuspto-grants-2006_01
ORD IDord-faa0bfa85b5447fd8f6ecb2ce92308e2
Source noteuspto-grants-2006_01