HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1612552Generated: October 26, 2026
1-Deoxy-1-(methylamino)hexitol → HCID 22252101, compound
https://huagongshe.com/reaction/1612552
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-Deoxy-1-(methylamino)hexitol | HCID 4049 | — |
| Reactant | 1-(4-Fluorophenyl)-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-[4-(10-iododecyloxy)phenyl]azetidin-2-one | HCID 22252035 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 22252101 | HCID 22252101 | — |
Reaction Steps
170 mg of 1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-[4-(10-iododecyloxy)phenyl]azetidin-2-one are dissolved in 5 ml of absolute dimethylformamide. 200 mg of 6-methylaminohexane-1,2,3,4,5-pentaol are then added, and the reaction solution is stirred at 50° C. for 2 h. After concentration using a rotary evaporator and oil pump pressure at 40° C., the residue is purified by preparative HPLC. The product is obtained as an oil. C41H56F2N2O8 (742) MS (ESI): M+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06992067B2 |
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| Source dataset | uspto-grants-2006_01 |
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| ORD ID | ord-3a953fc2f48c4fa7964eee9af3d0b5f6 |
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| Source note | uspto-grants-2006_01 |
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