Formaldehyde → HCID 19776189, compound

Participants

Reaction Steps

Thio-2-naphthol (16.0 g, 0.1 mol), 2,6-di-tertbutylphenol (20.6 g, 0.1 mol), paraformaldehyde (3.0 g, 0.1 mol) and di-n-butylamine (1 ml) in ethanol (100 ml) are heated, under reflux for thirteen hours, after which time thin layer chromatography shows the reaction to be complete. A small amount of solid impurity is filtered off and the solvent removed by rotary evaporation. A yellow oil is left which solidifies below 30° C. Petroleum (40°-60°) is added and a white solid (20.9 g, 55% of theory) of m.p. 30° C. is collected.

Provenance & Evidence