Formaldehyde → HCID 86746582, compound

HRID 1612595Notes

Reaction equation

HRID 1612595 reaction equation
[SH:1][C:2]1[O:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[C:11]([C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([CH3:21])[C:16]=1[OH:22])([CH3:14])([CH3:13])[CH3:12].C=O.[CH2:25](NCCCC)CCC>>[C:11]([C:15]1[CH:20]=[C:19]([CH:18]=[C:17]([CH3:21])[C:16]=1[OH:22])[CH2:25][C:7]1[C:5]2[NH:6][C:2](=[S:1])[O:3][C:4]=2[CH:10]=[CH:9][CH:8]=1)([CH3:14])([CH3:13])[CH3:12]

Participants

5

Reactant 4

HCID 712FormaldehydeHCID 8148DibutylamineHCID 166782-tert-Butyl-6-methylphenolHCID 1784182821,3-benzoxazole-2-thiol

Product 1

HCID 86746582HCID 86746582, compound

Procedure

2-Mercaptobenzoxazole (10.96 g, 0.073 mol), 2-tertbutyl-6-methylphenol (11.9 g, 0.073 mol), paraformaldehyde (2.18 g, 0.073 mol) and di-n-butylamine (0.5 ml) are heated to 120° C. After two hours, the reaction mixture solidifies. The solid mass is crystallised from ethanol to yield a white solid (19.8 g, 84% of theory) of m.p. 155°-157° C. (Found N=4.17; C19H21NO2S requires N=4.28%).

Workup

  1. customThe solid mass is crystallised from ethanol
  2. customto yield a white solid (19.8 g, 84% of theory) of m.p. 155°-157° C. (Found N=4.17; C19H21NO2S requires N=4.28%)

Sources & evidence

ORD record
ord-ab45366c1340438fa52e4b970170383a
Source dataset
uspto-grants-1993_03
Patent number
US05190723

Reaction notes

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