HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1612632Generated: November 1, 2026
Benzyl mercaptan → Methyl 2-benzylmercapto-3-nitrobenzoate
https://huagongshe.com/reaction/1612632
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzyl mercaptan | HCID 7509 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Methyl 2-chloro-3-nitrobenzoate | HCID 10751184 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Methyl 2-benzylmercapto-3-nitrobenzoate | HCID 54046874 | — |
Reaction Steps
45.4 g (0.21 mol) of 2-chloro-3-nitrobenzoic acid methyl ester and 24.8 ml (0.21 mol) of benzyl mercaptan are dissolved in 420 ml of dimethylformamide, and then 29.2 g (0.21 mol) of potassium carbonate are added and the batch is stirred for 8 hours at 80° C. It is then poured onto ice/water and extracted twice with ethyl acetate. The extracts are washed with water, dried over magnesium sulfate and concentrated by evaporation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05190928 |
|---|
| Source dataset | uspto-grants-1993_03 |
|---|
| ORD ID | ord-62edae93bebf434998964343d182cb02 |
|---|
| Source note | uspto-grants-1993_03 |
|---|
