HCID 19090048, compound → HCID 19090078, compound

Participants

Reaction Conditions

Reaction Steps

To 1.74 gm of 9-aminofuro[3,4-b]quinolin-1(3 H)-one was added 3.20 gm of 4-aminobutyl-1-benzylpiperidine, and the mixture was heated in a sealed tube for 6 hours at 200° C. while stirring. After cooling, the reaction mixture was recrystallized from ethyl acetate to obtain 3.00 gm of 9-amino- 2-(4-(1-benzYIpiperidYl)butyl)-2,3-dihydropyrrolo[3,4-b]quinolin-1-one (Compound (I) with R1 =R3 =H, R2 =NH2, A=>N-(CH2)n -, Y=>C=O, m=1, and n=4).

Provenance & Evidence