Ethanol → HCID 178476801, compound

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Reaction Steps

A solution of 14.42 g of ethyl (1,1-diethoxyethyl)-2-(4-chlorophenyl)prop-1-enylphosphinate in 50 ml of anhydrous dichloromethane containing 10% of absolute ethanol is treated with 6.518 g of trimethylchlorosilane. After stirring at room temperature for 24 hours the volatile material is removed under reduced pressure. Chromatography of the resulting oil on silica-gel gives ethyl 2-(4-chlorophenyl)prop-1-enylphosphinate as a colourless oil; 1H-NMR (CDCl3): δ(ppm)=7.35 (4H, m, Ph), 7.05 (1H, d, t, J=549 and 1.5 Hz, P--H), 5.56 (1H, d, CH), 5.30 (1H, d, CH), 4.20-3.97 (2H, q, CH2OP), 3.07 (2H, d, t, J=17+1.5 Hz, P--CH2), 1.27 (3H, t, CH3).

Provenance & Evidence