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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1612857Generated: November 3, 2026

4-hydroxy-1-[4-(2-nitrophenoxy)-2(E)-butenyl]piperidine → 4-di(3-thienyl)methoxy-1-[4-(2-nitrophenoxy)-2(E)-butenyl]piperidine

https://huagongshe.com/reaction/1612857

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-hydroxy-1-[4-(2-nitrophenoxy)-2(E)-butenyl]piperidineHCID 19776719—
ReactantDi(3-thienyl)methyl chlorideHCID 19776723—
Product4-di(3-thienyl)methoxy-1-[4-(2-nitrophenoxy)-2(E)-butenyl]piperidineHCID 19776720—

Reaction Steps

The procedure of Example 39 (a) was repeated except for using di(3-thienyl)methyl chloride and 4-hydroxy-1-[4-(2-nitrophenoxy)-2(E)-butenyl]piperidine instead of phenyl-2-thienylmethyl chloride and 4-hydroxy-1-[4-(2-nitrophenoxy)-2(E)-butenyl]piperidine to give oily 4-di(3-thienyl)methoxy-1-[4-(2-nitrophenoxy)-2(E)-butenyl]piperidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05190959
Source datasetuspto-grants-1993_03
ORD IDord-72c1bb7c3301450eb21e352fe5f19ddb
Source noteuspto-grants-1993_03