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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1612862Generated: November 1, 2026

Di(3-thienyl)methyl chloride → 4-Di(3-thienyl)methoxy-1-[2-methyl-3-(2-nitrophenoxy)propyl]piperidine

https://huagongshe.com/reaction/1612862

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDi(3-thienyl)methyl chlorideHCID 19776723—
Reactant4-Hydroxy-1-[2-methyl-3-(2-nitrophenoxy)propyl]piperidineHCID 19776783—
Reactant4-Hydroxy-1-[3-(2-nitrophenoxy)propyl]piperidineHCID 19776793—
Product4-Di(3-thienyl)methoxy-1-[2-methyl-3-(2-nitrophenoxy)propyl]piperidineHCID 19776841—

Reaction Steps

The procedure of Example 36 (a) was repeated except for using di(3-thienyl)methyl chloride and 4-hydroxy-1-[2-methyl-3-(2-nitrophenoxy)propyl]piperidine instead of phenyl-2-thienylmethyl chloride and 4-hydroxy-1-[3-(2-nitrophenoxy)propyl]piperidine to give oily 4-di(3-thienyl)methoxy-1-[2-methyl-3-(2-nitrophenoxy)propyl]piperidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05190959
Source datasetuspto-grants-1993_03
ORD IDord-235b8115dba8468f819415cf8240954d
Source noteuspto-grants-1993_03