Pyridine → Methyl 5-(1,1-dioxido-5-methyl-4-oxo-1,2,5-thiadiazepan-2-yl)-8-hydroxy[1,6]-naphthyridine-7-carboxylate

HRID 161287Notes

Reaction equation

HRID 161287 reaction equation
[Br:1][c:2]1[c:3]2[cH:4][cH:5][cH:6][n:7][c:8]2[c:9]([OH:16])[c:10]([C:12](=[O:13])[O:14][CH3:15])[n:11]1.[CH3:17][N:18]1[C:19](=[O:27])[CH2:20][NH:21][S:22](=[O:25])(=[O:26])[CH2:23][CH2:24]1.[cH:28]1[cH:29][cH:30][n:31][cH:32][cH:33]1>>[c:2]1([N:21]2[CH2:20][C:19](=[O:27])[N:18]([CH3:17])[CH2:24][CH2:23][S:22]2(=[O:25])=[O:26])[c:3]2[cH:4][cH:5][cH:6][n:7][c:8]2[c:9]([OH:16])[c:10]([C:12](=[O:13])[O:14][CH3:15])[n:11]1

Participants

4

Reactant 3

HCID 1049PyridineHCID 22343006Methyl 5-bromo-8-hydroxy-1,6-naphthyridine-7-carboxylateHCID 223463175-Methyl-1,2,5-thiadiazepan-4-one 1,1-dioxide

Product 1

HCID 22346441Methyl 5-(1,1-dioxido-5-methyl-4-oxo-1,2,5-thiadiazepan-2-yl)-8-hydroxy[1,6]-naphthyridine-7-carboxylate

Sources & evidence

ORD record
ord-bb391164447247ca98f8d8411773eadc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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