HCID 19776904, compound → HCID 19776910, compound

Participants

Reaction Steps

1.08 g (3.94 mmol) of the compound from Example 5 and 2 g (2.6 mmol) of the compound from Example 16 and 30 mg of tetrakis(triphenylphosphine)palladium are heated under reflux in 40 ml of toluene under a nitrogen atmosphere for 50 h. After concentrating in vacuo, the residue is taken up in acetonitrile and washed five times with pentane. The acetonitrile phase is concentrated in vacuo and the remaining oil (1.33 g) is chromatographed on a silica gel column using ethyl acetate/petroleum ether 1:5.

Provenance & Evidence