Dodecanedioic acid monomethyl ester → 12-Hydroxydodecanoic Acid

HRID 1612941Notes

Reaction equation

HRID 1612941 reaction equation
C[O:2][C:3](=[O:17])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][C:14](O)=[O:15].COC(=O)CCCCCCCCCCCCCC(O)=O>>[CH2:9]([CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][OH:15])[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][C:3]([OH:17])=[O:2]

Participants

3

Reactant 2

HCID 231998Dodecanedioic acid monomethyl esterHCID 9947818HCID 9947818, compound

Product 1

HCID 7903412-Hydroxydodecanoic AcidYield 37%

Procedure

The same procedure as in Example 12 was repeated except that a barium salt of dodecanedioic acid monomethyl ester (20 mmol) was used instead of the barium salt of pentadecanedioic acid monomethyl ester, and the amount of the catalyst was 0.31 g to obtain ω-hydroxy dodecanoic acid. The yield was 37%.

Sources & evidence

ORD record
ord-c637075d79c74cc89ac08670f83a86d8
Source dataset
uspto-grants-1993_03
Patent number
US05191096

Reaction notes

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