反应详情

温度

100 °C

N-Benzyl-2-methoxymethylmorpholine (412.3 g) is dissolved in methanol (2 liters), and thereto is added 10% palladium-carbon (33 g), and the mixture is stirred under hydrogen pressure of 9 kg/cm2 at 100° C. After completion of the reaction, palladium-carbon is filtered off, and the solvent is distilled off under atmospheric pressure to give a pale yellow oily substance. The oily substance is distilled under reduced pressure to give the title compound (212.3 g) as colorless liquid.

1. filtrationis filtered off
2. distillationthe solvent is distilled off under atmospheric pressure
3. customto give a pale yellow oily substance
4. distillationThe oily substance is distilled under reduced pressure