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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1612956Generated: November 2, 2026

Hydrochloric Acid → Morpholin-2-ylmethanol hydrochloride

https://huagongshe.com/reaction/1612956

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantEthanolHCID 702—
Reactant(4-Benzylmorpholin-2-yl)methanolHCID 2776358—
ProductMorpholin-2-ylmethanol hydrochlorideHCID 19777263—

Reaction Steps

N-Benzyl-2-hydroxymethylmorpholine prepared in the same manner as described in Synthetic Communication, Vol. 10 (1), pages 59-73, 1980 (1.3 g) is subjected to hydrogenolysis in hydrogen chloride-containing ethanol in the same manner as described in Reference Example 15 to give 2-hydroxymethylmorpholine hydrochloride (1.3 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05191079
Source datasetuspto-grants-1993_03
ORD IDord-806570b9553b46f3b22cf0de3da44dc2
Source noteuspto-grants-1993_03