HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl chloroformate → Carbonic acid, 2-bromo-4-fluorophenyl methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl chloroformate | HCID 6586 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2-Bromo-4-fluorophenol | HCID 605472 | — |
| Solvent | Water | HCID 962 | — |
| Product | Carbonic acid, 2-bromo-4-fluorophenyl methyl ester | HCID 13268177 | — |
Reaction Steps
2-Bromo-4-fluorophenol (28 g) was added to a solution of sodium hydroxide (7 g) in water (100 ml), and methyl chloroformate was dropwise added thereto at a temperature of below 10° C. Precipitated crystals were collected by filtration and washed with water to give methyl (2-bromo-4-fluorophenyl) carbonate (41 g). M.P., 80.7° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05191105 |
| Source dataset | uspto-grants-1993_03 |
| ORD ID | ord-39531f67960b4ceca48960b42212834c |
| Source note | uspto-grants-1993_03 |