HCID 18954484, compound → HCID 18954485, compound

Participants

Reaction Steps

Into a 50 ml egg plant type flask equipped with a magnetic stirrer, a dropping funnel, a reflux condenser, and a nitogen-inlet tube, were charged 250 mg of 5% palladium/carbon and 5.0 gm (24 mmol) of 1-(4-allyloxy-3-methoxyphenyl)- 4,4-dimethylpentane-1,3-dione which had been dispersed in 25 ml of ethanol. After completely replacing the reaction atmosphere by hydrogen, the mixture was stirred for 2 hours at room temperature. Palladium/carbon was removed by filtration and the solvent was evaporated to obtain pale yellow oily product. The oil was submitted to silica gel column chromatography using a hexane-ethyl acetate (10:1-5:1) mixed solvent as an eluent to produce 4.0 gm (yield: 80%) of the title compound as a colorless solid.

Provenance & Evidence