HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Iodide → 4-[6-(2,3-Dimethoxyphenyl)hexyloxy]-3,5-dipropylbenzoic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Benzoic acid, 3,5-dipropyl-4-hydroxy-, ethyl ester | HCID 57881 | — |
| Reactant | 1-(6-Bromohexyl)-2,3-dimethoxybenzene | HCID 14986283 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 4-[6-(2,3-Dimethoxyphenyl)hexyloxy]-3,5-dipropylbenzoic acid ethyl ester | HCID 14986323 | — |
Reaction Steps
A mixture of 1.20 (4.0 mmol) of 1-(6-bromohexyl)-2,3-dimethoxybenzene, 1.00 g (4.0 mmol) of 3,5-dipropyl-4-hydroxybenzoic acid ethyl ester, 1.10 g (8 mmol) of potassium carbonate and 0.6 g (4 mmol) of sodium iodide in 35 mL of acetone was stirred at reflux for 47 hours. Workup and purification as in Example 16 gave 4-[6-(2,3-dimethoxyphenyl)hexyloxy]-3,5-dipropylbenzoic acid ethyl ester as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05191108 |
| Source dataset | uspto-grants-1993_03 |
| ORD ID | ord-4c662896710943c08a168b3c4d180ccf |
| Source note | uspto-grants-1993_03 |