4-[6-(2,3-Dimethoxyphenyl)hexyloxy]-3,5-dipropylbenzoic acid ethyl ester → 4-[6-(2,3-Dimethoxyphenyl)hexyloxy]-3,5-dipropylbenzoic acid

HRID 1613053Notes

Reaction equation

HRID 1613053 reaction equation
C([O:3][C:4](=[O:34])[C:5]1[CH:10]=[C:9]([CH2:11][CH2:12][CH3:13])[C:8]([O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][C:21]2[CH:26]=[CH:25][CH:24]=[C:23]([O:27][CH3:28])[C:22]=2[O:29][CH3:30])=[C:7]([CH2:31][CH2:32][CH3:33])[CH:6]=1)C>CO.[OH-].[Na+]>[CH3:30][O:29][C:22]1[C:23]([O:27][CH3:28])=[CH:24][CH:25]=[CH:26][C:21]=1[CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][O:14][C:8]1[C:9]([CH2:11][CH2:12][CH3:13])=[CH:10][C:5]([C:4]([OH:34])=[O:3])=[CH:6][C:7]=1[CH2:31][CH2:32][CH3:33]

Participants

4

Reactant 1

HCID 149863234-[6-(2,3-Dimethoxyphenyl)hexyloxy]-3,5-dipropylbenzoic acid ethyl ester

Product 1

HCID 149863244-[6-(2,3-Dimethoxyphenyl)hexyloxy]-3,5-dipropylbenzoic acid

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 14798Sodium HydroxideSolvent

Procedure

A solution of 1.8 g of 4-[6-(2,3-dimethoxyphenyl)hexyloxy]-3,5-dipropylbenzoic acid ethyl ester in 100 mL of methanol and 20 mL of 1N sodium hydroxide was stirred at reflux for 3 hours. Workup as in Example 24 gave 4-[6-(2,3-dimethoxyphenyl)hexyloxy]-3,5-dipropylbenzoic acid, mp 61°-65°.

Workup

  1. temperatureat reflux for 3 hours

Sources & evidence

ORD record
ord-7b43dfae8f9240e882e8064df7055d42
Source dataset
uspto-grants-1993_03
Patent number
US05191108

Reaction notes

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