HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[6-(2,3-Dimethoxyphenyl)hexyloxy]-2-hydroxybenzoic acid methyl ester → 4-[6-(2,3-Dimethoxyphenyl)hexyloxy]-2-hydroxybenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[6-(2,3-Dimethoxyphenyl)hexyloxy]-2-hydroxybenzoic acid methyl ester | HCID 14986338 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | 4-[6-(2,3-Dimethoxyphenyl)hexyloxy]-2-hydroxybenzoic acid | HCID 14986339 | 82% |
Reaction Steps
A solution of 0.45 g (1.2 mmol) of 4-[6-(2,3-dimethoxyphenyl)hexyloxy]-2-hydroxybenzoic acid methyl ester in 25 mL of methanol and 8 mL of 1N sodium hydroxide was refluxed for 7 hours. Workup as in Example 24 and recrystallization from methanol gave 0.36 g (82% yield), mp 115°-116° of 4-[6-(2,3-dimethoxyphenyl)hexyloxy]-2-hydroxybenzoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05191108 |
| Source dataset | uspto-grants-1993_03 |
| ORD ID | ord-9833d657bf184a2294b5f3b8e7a15464 |
| Source note | uspto-grants-1993_03 |