HCID 5479375, compound → HCID 5479357, compound

Participants

Reaction Steps

The product of Step J, 85 mg was dissolved in 10 mL of methanol and 10 mL of THF, and to it was added 0.10 g of 10% palladium on carbon. The mixture was stirred under an atmosphere of hydrogen for 48 hours at room temperature, then filtered and concentrated to dryness. The residue was dissolved in 10 mL of hot ethanol and 20 mL water was added. On cooling the white solid precipitate was collected and dried under vacuum over P2O5. The yield was 72 mg (98% yield) of pure product: mp 218°-219° C. (effervesces, sinters at 215) elemental analysis, Calc'd for C33H40N2O6 : (560.696): C, 70.69; H, 7.19; N, 5.00; Found: C, 70.62; H, 7.39; N, 4.79.

Provenance & Evidence