Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | Acrylamide | HCID 6579 | — |
| Reactant | 1,5-Diazabicyclo(5,4,0)undec-5-ene | HCID 314112 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 3-(1H-Imidazol-1-yl)propanamide | HCID 14088730 | — |
Reaction Steps
A stirred mixture of 3.4 g (49.9 mmoles) of imidazole, 3.55 g (49.9 mmoles) of acrylamide, and 7.6 g (49.9 mmoles) of 1,5-diazabicyclo[5.4.0]undec-5-ene (DBu) in 100 mL of sieve dried acetonitrile was heated at 80° C. under nitrogen for 2.0 hours. The mixture was let cool, where upon the product crystallized out of the solution.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05192758 |
|---|
| Source dataset | uspto-grants-1993_03 |
|---|
| ORD ID | ord-fe4af142571142b3bfd884fe936ec5f1 |
|---|
| Source note | uspto-grants-1993_03 |
|---|
