Hydrazine hydrate (1:1) → 4-Hydrazinyl-1-propylquinolin-2(1H)-one

Participants

Reaction Steps

In 140 ml of ethanol was dissolved 6.02 g (27 mmol) of 4-chloro-1-propylquinolin-2(1H)-one, and 140 ml of hydrazine monohydrate was added thereto, followed by refluxing for 3 hours. The reaction mixture was concentrated to an about half of its original volume and then allowed to cool to obtain 5.53 g (94%) of the titled compound as a pale yellow crystal.

Provenance & Evidence