1-(2-Bromoethyl)-4-methoxybenzene → 1-Diphenylmethoxy-2-(4-methoxyphenethylamino)-2-methylpropane

HRID 1613172Notes

Reaction equation

HRID 1613172 reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([CH2:7][CH2:8]Br)=[CH:5][CH:4]=1.[NH2:12][C:13]([CH3:30])([CH3:29])[CH2:14][O:15][CH:16]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[C:17]1([CH:16]([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[O:15][CH2:14][C:13]([NH:12][CH2:8][CH2:7][C:6]2[CH:10]=[CH:11][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)([CH3:30])[CH3:29])[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1

Participants

3

Reactant 2

HCID 844271-(2-Bromoethyl)-4-methoxybenzeneHCID 197753022-Amino-1-diphenylmethoxy-2-methylpropane

Product 1

HCID 197753321-Diphenylmethoxy-2-(4-methoxyphenethylamino)-2-methylpropane

Procedure

The title compound was prepared as described in Example 1 using 4-methoxyphenethyl bromide and 2-amino-1-diphenylmethoxy-2-methylpropane (see Preparation 1). The title compound was obtained as a colourless oil (378 mg, 33%).

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-f85969f36ece46f5a24ff140ee596a3b
Source dataset
uspto-grants-1993_03
Patent number
US05192765

Reaction notes

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