1-(2-Bromoethyl)-4-methoxybenzene → 1-Diphenylmethoxymethyl-1-(4-methoxyphenethylamino)cyclohexane

HRID 1613174Notes

Reaction equation

HRID 1613174 reaction equation
[NH2:1][C:2]1([CH2:8][O:9][CH:10]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1.[CH3:23][O:24][C:25]1[CH:33]=[CH:32][C:28]([CH2:29][CH2:30]Br)=[CH:27][CH:26]=1>>[C:11]1([CH:10]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[O:9][CH2:8][C:2]2([NH:1][CH2:30][CH2:29][C:28]3[CH:32]=[CH:33][C:25]([O:24][CH3:23])=[CH:26][CH:27]=3)[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]2)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

3

Reactant 2

HCID 844271-(2-Bromoethyl)-4-methoxybenzeneHCID 197753071-Amino-1-diphenylmethoxymethylcyclohexane

Product 1

HCID 197753001-Diphenylmethoxymethyl-1-(4-methoxyphenethylamino)cyclohexane

Procedure

The title compound was prepared as described in Example 1 using 1-amino-1-diphenylmethoxymethylcyclohexane (see Preparation 3) and 4-methoxyphenethyl bromide. The title compound was obtained as a colourless oil (0.88 g, 68%) which was characterised from its 1H-n.m.r. spectrum.

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-3c85d169c1054edaa26fb33307ec76a2
Source dataset
uspto-grants-1993_03
Patent number
US05192765

Reaction notes

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