1-Diphenylmethoxy-2-(4-methoxyphenethylamino)-2-methylpropane → 1-Diphenylmethoxy-2-[N-(4-methoxyphenethyl)-N-methylamino]-2-methylpropane

HRID 1613176Notes

Reaction equation

HRID 1613176 reaction equation
[C:1]1([CH:7]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[O:8][CH2:9][C:10]([NH:13][CH2:14][CH2:15][C:16]2[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[CH:18][CH:17]=2)([CH3:12])[CH3:11])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:30]([BH3-])#N.[Na+].C=O>>[C:24]1([CH:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[O:8][CH2:9][C:10]([N:13]([CH2:14][CH2:15][C:16]2[CH:17]=[CH:18][C:19]([O:22][CH3:23])=[CH:20][CH:21]=2)[CH3:30])([CH3:11])[CH3:12])[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1

Participants

3

Reactant 2

HCID 197753321-Diphenylmethoxy-2-(4-methoxyphenethylamino)-2-methylpropaneHCID 131717802Sodium cyanoborohydride formaldehyde

Product 1

HCID 197753191-Diphenylmethoxy-2-[N-(4-methoxyphenethyl)-N-methylamino]-2-methylpropane

Procedure

The title compound was prepared as described in Example 5, Method A, using 1-diphenylmethoxy-2-(4-methoxyphenethylamino)-2-methylpropane (see Example 2) and sodium cyanoborohydride/formaldehyde. The title compound was obtained as a colourless oil (200 mg, 69%).

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-b1f801d918734ef8bec278fec03ee43d
Source dataset
uspto-grants-1993_03
Patent number
US05192765

Reaction notes

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