Benzhydrol → 1-Amino-1-diphenylmethoxymethylcyclohexane

HRID 1613186Notes

Reaction equation

HRID 1613186 reaction equation
[NH2:1][C:2]1([CH2:8][OH:9])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1.[CH:10](O)([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[NH2:1][C:2]1([CH2:8][O:9][CH:10]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 7037BenzhydrolHCID 409153(1-Aminocyclohexyl)methanol

Product 1

HCID 197753071-Amino-1-diphenylmethoxymethylcyclohexane

Procedure

This was prepared as described in Preparation 1 using 1-aminocyclohexane-1-methanol and benzhydrol. The title compound was obtained as a pale yellow oil (2.02 g, 68%), which was characterised by its 1H-n.m.r. spectrum.

Workup

  1. customThis was prepared

Sources & evidence

ORD record
ord-a09cfb4736e54dfca6486f359f584e88
Source dataset
uspto-grants-1993_03
Patent number
US05192765

Reaction notes

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