HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl formate → 1-Diphenylmethoxy-2-formylamino-2-methylpropane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl formate | HCID 8025 | — |
| Reactant | 2-Amino-1-diphenylmethoxy-2-methylpropane | HCID 19775302 | — |
| Product | 1-Diphenylmethoxy-2-formylamino-2-methylpropane | HCID 19775310 | 99.6% |
Reaction Steps
A mixture of 2-amino-1-diphenylmethoxy-2-methylpropane (7.6 g -- see Preparation 1) and ethyl formate (6.7 g) was heated at 100° in a steel bomb for 18 hours and evaporated. The residue was purified by chromatography on silica (18 g) using hexane plus 0-100% methylene chloride as the eluant. Appropriate fractions were combined and evaporated to give the title compound as a colourless gum (8.4 g, 99%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05192765 |
| Source dataset | uspto-grants-1993_03 |
| ORD ID | ord-ab78bc85368441a587b0bf79f89c674b |
| Source note | uspto-grants-1993_03 |