HCID 19749645, compound → HCID 19749619, compound

HRID 1613205Notes

Reaction equation

HRID 1613205 reaction equation
Cl.[S:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[N:4]=[C:3]1[N:11]1[CH2:16][CH2:15][CH:14]([CH2:17][NH2:18])[CH2:13][CH2:12]1>[OH-].[Na+]>[S:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[N:4]=[C:3]1[N:11]1[CH2:12][CH2:13][CH:14]([CH2:17][NH2:18])[CH2:15][CH2:16]1

Participants

3

Reactant 1

HCID 19749645HCID 19749645, compound

Product 1

HCID 19749619HCID 19749619, compound

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

The compound of Example 1 is taken up in 1 N caustic soda. The expected product is then obtained after extraction with dichloromethane. After drying, the organic phase is filtered and evaporated. The oil thus obtained is taken up in boiling hexane. After cooling, the product crystallizes.

Sources & evidence

ORD record
ord-66e833ba66e640618db2802f1ba5986a
Source dataset
uspto-grants-1993_03
Patent number
US05192775

Reaction notes

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