HCID 19775547, compound → HCID 19775542, compound

HRID 1613248Notes

Reaction equation

HRID 1613248 reaction equation
[CH3:1][C:2]1[S:3][C:4]([CH2:12][C:13]2[CH:18]=[CH:17][C:16]([N+:19]([O-])=O)=[CH:15][CH:14]=2)=[C:5]([CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])[N:6]=1>C(O)C>[CH3:1][C:2]1[S:3][C:4]([CH2:12][C:13]2[CH:14]=[CH:15][C:16]([NH2:19])=[CH:17][CH:18]=2)=[C:5]([CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])[N:6]=1

Participants

3

Reactant 1

HCID 19775547HCID 19775547, compound

Product 1

HCID 19775542HCID 19775542, compoundYield 91.1%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

1.7 g of 2-methyl-5-(4-nitrobenzyl)-4-pentylthiazole (5.6 mmol) in 100 ml of ethanol are hydrogenated according to Example 25 to give 1.4 g of 2-methyl-5-(4-aminobenzyl)-4-pentylthiazole in the form of a colorless oil.

Sources & evidence

ORD record
ord-c34e9ae13c7d4539b0b33f1ad3a5a737
Source dataset
uspto-grants-1993_03
Patent number
US05192781

Reaction notes

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