HCID 19775548, compound → HCID 19775549, compound

HRID 1613251Notes

Reaction equation

HRID 1613251 reaction equation
[NH2:1][C:2]1[S:3][C:4]([CH2:12][C:13]2[CH:18]=[CH:17][C:16]([N+:19]([O-])=O)=[CH:15][CH:14]=2)=[C:5]([CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])[N:6]=1>C(O)C>[NH2:1][C:2]1[S:3][C:4]([CH2:12][C:13]2[CH:18]=[CH:17][C:16]([NH2:19])=[CH:15][CH:14]=2)=[C:5]([CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])[N:6]=1

Participants

3

Reactant 1

HCID 19775548HCID 19775548, compound

Product 1

HCID 19775549HCID 19775549, compoundYield 111.2%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

3.0 g of 2-amino-5-(4-nitrobenzyl)-4-pentylthiazole (9.8 mmol) in 100 ml of ethanol are hydrogenated according to Example 25 to give 3 g of 2-amino-5-(4-aminobenzyl)-4-pentylthiazole in the form of a brown oil.

Sources & evidence

ORD record
ord-dfa32d2109754f43964b690ef834f3e1
Source dataset
uspto-grants-1993_03
Patent number
US05192781

Reaction notes

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