1-Bromo-3-chloropropane → HCID 53960089, compound

Participants

Reaction Steps

A mixture of 30 g 0.19 mole) of 1-bromo-3-chloropropane, 25 g (0.17 mole) of ethylheptylamine, 28 g (0.20 mole) of potassium carbonate and 250 ml of toluene was refluxed for 8 hours. After cooling, the solid was collected by filtration, and concentrated. The residue was purified by silica gel column chromatography (ethyl acetate) to give 17 g of the desired compound (yield 44%).

Provenance & Evidence