反应详情

The title compound was prepared by procedures of Example 22 from sulfamoyl chloride and 3-phenoxy-2-propanol through the partitioning and final evaporation to give an oil as residue. The oil was purified by chromatography using a 4.5 cm×100 cm glass column packed with 500 g of silica gel and methylene chloride as eluting agent. Fractions containing the title compound were combined and the solvent was evaporated under reduced pressure to give a 37% yield of an oil which solidified on standing, mp 57°-60° C.

1. customevaporation
2. customto give an oil as residue
3. customThe oil was purified by chromatography
4. washas eluting agent
5. additionFractions containing the title compound
6. customthe solvent was evaporated under reduced pressure