Toluene → 3-Bromophenyl sulfamate

HRID 1613416Notes

Reaction equation

HRID 1613416 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([OH:8])[CH:5]=[CH:6][CH:7]=1.Cl[S:10]([N:13]=C=O)(=[O:12])=[O:11].C1(C)C=CC=CC=1>C1C=CC=CC=1>[Br:1][C:2]1[CH:3]=[C:4]([O:8][S:10](=[O:12])(=[O:11])[NH2:13])[CH:5]=[CH:6][CH:7]=1

Participants

5

Reactant 3

HCID 1140TolueneHCID 115633-BromophenolHCID 70918Chlorosulfonyl isocyanate

Product 1

HCID 444592333-Bromophenyl sulfamateYield 78.5%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

This compound was prepared according to the procedure used in Example 75. A mixture of 17.3 g (0.1 mole) of 3-bromophenol, 9.1 ml (14.8 g, 0.105 mole) of chlorosulfonyl isocyanate and 100 ml of toluene gave 19.8 g (70%) of white solid, mp 90°-91.5° C. (benzene).

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-f596a7ac04b04fe99457431eb044a02b
Source dataset
uspto-grants-1993_03
Patent number
US05192785

Reaction notes

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