Chlorosulfonyl isocyanate → HCID 46883000, compound

HRID 1613432Notes

Reaction equation

HRID 1613432 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([OH:9])[CH:5]=[C:6]([F:8])[CH:7]=1.Cl[S:11]([N:14]=C=O)(=[O:13])=[O:12]>C1(C)C=CC=CC=1>[F:1][C:2]1[CH:3]=[C:4]([O:9][S:11](=[O:13])(=[O:12])[NH2:14])[CH:5]=[C:6]([F:8])[CH:7]=1

Participants

4

Reactant 2

HCID 70918Chlorosulfonyl isocyanateHCID 759283,5-Difluorophenol

Product 1

HCID 46883000HCID 46883000, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Using the procedure of Example 75, the title compound was prepared using a mixture of 9.9 g (0.076 mole) of 3,5-difluorophenol and 7.0 ml (0.08 mole) of chlorosulfonyl isocyanate in 50 ml of toluene. The solid product was recrystallized from benzene to yield 11.7 g (74%) of white solid, mp 85°-88° C.

Workup

  1. customThe solid product was recrystallized from benzene

Sources & evidence

ORD record
ord-b4a6fe4d939a47a7b519470c5ad4546c
Source dataset
uspto-grants-1993_03
Patent number
US05192785

Reaction notes

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