HCID 19773959, compound → HCID 178443049, compound

HRID 1613534Notes

Reaction equation

HRID 1613534 reaction equation
O[C:2]1[C:6](O)([C:7]2[CH:12]=[CH:11][CH:10]=[C:9]([O:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])[CH:8]=2)[N:5]([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[NH:4][C:3]=1[OH:37]>[O-2].[O-2].[Mn+4].C1(C)C=CC=CC=1>[CH2:14]([O:13][C:9]1[CH:8]=[C:7]([C:6]2[N:5]([C:31]3[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=3)[N:4]=[C:3]([OH:37])[CH:2]=2)[CH:12]=[CH:11][CH:10]=1)[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29]

Participants

4

Reactant 1

HCID 19773959HCID 19773959, compound

Product 1

HCID 178443049HCID 178443049, compound

Reagents, catalysts & solvents 2

HCID 178418406HCID 178418406, compoundCatalystHCID 1140TolueneSolvent

Procedure

60 ml of toluene and 10 g (0.12 mol) of manganese dioxide were added to 6.3 g (0.013 mol) of 4,5-dihydroxy-5-(3-hexadecyloxyphenyl)-3-hydroxy-1-phenylpyrazole and, heated and stirred for 2 hours on a steam bath. After inorganic substances were filtrated out, the remaining filtrate was concentrated and dried to a solid, and the solid product was crystallized in 20 ml of ethyl acetate. The product crystallized had a melting point of from 108° to 109° C. Yield: 5.8 g, 92.5%.

Workup

  1. temperatureheated
  2. filtrationAfter inorganic substances were filtrated out
  3. concentrationthe remaining filtrate was concentrated
  4. customdried to a solid
  5. customthe solid product was crystallized in 20 ml of ethyl acetate
  6. customThe product crystallized
  7. customof from 108° to 109° C

Sources & evidence

ORD record
ord-74e4cbb57dee4fbc988c29d1c4ff54ca
Source dataset
uspto-grants-1993_03
Patent number
US05194348

Reaction notes

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