HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propylene Oxide → 2-Isopropylcyclohexan-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propylene Oxide | HCID 6378 | — |
| Reactant | 1,2-Epoxybutane | HCID 7834 | — |
| Reactant | 2-tert-Butylcyclohexanol | HCID 26068 | — |
| Reactant | 2-Isopropylcyclohexan-1-ol | HCID 95331 | — |
| Product | 2-Isopropylcyclohexan-1-ol | HCID 95331 | — |
| Product | 1-(2-Isopropylcyclohexyloxy)-2-butanol | HCID 19774066 | — |
Reaction Steps
The synthesis was carried out in the same manner as described in Example 1, except that 20.0 g (0.141 mol) of 2-isopropylcyclohexanol (cis:trans=6:4) and 10.1 g (0.141 mol) of 1,2-butyleneoxide were used instead of 30.0 g (0.192 mol) of 2-tert-butylcyclohexanol (cis:trans=8:2) and 11.1 g (0.192 mol) of propyleneoxide. 6.5 g of 2-isopropylcyclohexanol and 16.6 g of 1-(2-isopropylcyclohexyloxy)-2-butanol (cis:trans=6:4) were obtained in a 55% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05194423 |
| Source dataset | uspto-grants-1993_03 |
| ORD ID | ord-2e7b5d8173444c7da53deafd40610bef |
| Source note | uspto-grants-1993_03 |