2-Indanyl p-toluenesulfonate → HCID 67788482, compound

HRID 1613569Notes

Reaction equation

HRID 1613569 reaction equation
[O:1]1[C:7]2[CH:8]=[CH:9][CH:10]=[C:11]([N:12]3[CH2:17][CH2:16][N:15](C4CC5C(=CC=CC=5)C4)[CH2:14][CH2:13]3)[C:6]=2[O:5][CH:4]=[CH:3][CH2:2]1.S(C1C=CC(C)=CC=1)(OC1CC2C(=CC=CC=2)C1)(=O)=O>>[O:1]1[C:7]2[CH:8]=[CH:9][CH:10]=[C:11]([N:12]3[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]3)[C:6]=2[O:5][CH:4]=[CH:3][CH2:2]1

Participants

3

Reactant 2

HCID 70214742-Indanyl p-toluenesulfonateHCID 67788284HCID 67788284, compound

Product 1

HCID 67788482HCID 67788482, compoundYield 20%

Procedure

4-[benzo(1,5)dioxepin-6-yl]-1-(indan-2-yl)-piperazine, m.p. (M.K): 138°-140° C., from indan-2-yl tosylate and N-[benzo(1,5)dioxepin-6-yl]-piperazine [cf. J. Med. Chem. (1988), p. 1935] (yield: 20%).

Workup

  1. custom138°-140° C.

Sources & evidence

ORD record
ord-5ca46f843fcb4f61be6eeb4c7ccda59c
Source dataset
uspto-grants-1993_03
Patent number
US05194437

Reaction notes

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