HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Iodide → Batoprazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Bis(2-chloroethyl)amine hydrochloride | HCID 522769 | — |
| Reactant | 8-Aminocoumarin | HCID 12666551 | — |
| Solvent | Chlorobenzene | HCID 7964 | — |
| Product | Batoprazine | HCID 184839 | — |
Reaction Steps
N-(coumarin-8-yl)-piperazine was prepared by reacting 8-aminocoumarin with an excess of bis(2-chloroethyl)amine hydrochloride in the presence of potassium carbonate and then of potassium iodide, the reaction being carried out under reflux in chlorobenzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05194437 |
| Source dataset | uspto-grants-1993_03 |
| ORD ID | ord-f8533c2bb7764576924fa62b38338bd6 |
| Source note | uspto-grants-1993_03 |