HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-(Benzodioxan-5-yl)-1-[3-(indan-2-yl)propionyl]-piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1H-Indene-3-acetic acid | HCID 3014022 | — |
| Reactant | 4-(Benzodioxan-5-yl)-1-[3-(indan-2-yl)-propyl]piperazine | HCID 10068238 | — |
| Product | 4-(Benzodioxan-5-yl)-1-[3-(indan-2-yl)propionyl]-piperazine | HCID 10408215 | 50% |
Reaction Steps
4-(benzodioxan-5-yl)-1-[3-(indan-2-yl)-propyl]piperazine and its hydrochloride, m.p. (K): 210° C., by reduction of 4-(benzodioxan-5-yl)-1-[3-(indan-2-yl)propionyl]-piperazine (yield: 50%), which was itself prepared in a yield of 86% from 3-(indan-2-yl)-propionic acid, m.p. (K): 75°-78° C., and N-(benzodioxan-5-yl)piperazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05194437 |
| Source dataset | uspto-grants-1993_03 |
| ORD ID | ord-32f90fd600ab4641b506b831152bb38f |
| Source note | uspto-grants-1993_03 |