HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 5,6,7,8-Tetrahydro-4-methyl-7-(1-propylamino)quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 5,6,7,8-tetrahydro-7-(N-hydroxy-1-propylamino)-4-methylquinoline | HCID 14835950 | — |
| Catalyst | titanium(III) trichloride | HCID 10313229 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5,6,7,8-Tetrahydro-4-methyl-7-(1-propylamino)quinoline | HCID 14835951 | — |
Reaction Steps
This compound was prepared from the product of Step 7 (4.4 g, 20 mmol), titanium trichoride, 20 wt. % solution in 20-30 wt. % hydrochloric acid (23 ml, 30 mmol), and methanol (50 ml) using the procedure described in Example 11. The crude product (4.2 g, 81%) was converted into the product of Step 9 without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05194439 |
| Source dataset | uspto-grants-1993_03 |
| ORD ID | ord-302e44be96d742b5954eb4d389f20f32 |
| Source note | uspto-grants-1993_03 |