5,6-Dihydroquinoline → 5,6,7,8-Tetrahydro-7-dimethylaminoquinoline

HRID 1613595Notes

Reaction equation

[Cl-].[CH3:2][NH2+:3][CH3:4].[N:5]1[C:14]2[CH:13]=[CH:12][CH2:11][CH2:10][C:9]=2[CH:8]=[CH:7][CH:6]=1>>[CH3:2][N:3]([CH3:4])[CH:12]1[CH2:13][C:14]2[N:5]=[CH:6][CH:7]=[CH:8][C:9]=2[CH2:10][CH2:11]1

Participants

Reactant 2

HCID 123183175,6-Dihydroquinoline

HCID 12954980Dimethylazanium;chloride

Product 1

HCID 148359225,6,7,8-Tetrahydro-7-dimethylaminoquinoline

Procedure

This compound was prepared from dimethylammonium chloride (1.63 g, 20 mmol) and 5,6-dihydroquinoline (1.31 g, 10 mmol) using the experimental and purification method describes in Example 48. The product (0.72 g) was an oil which was identical to the compound isolated in Example 3.

Workup

custompurification method

Sources & evidence

ORD record: ord-d2d2415ca6bc447c84f1eb4ef37e354c
Source dataset: uspto-grants-1993_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05194439

Reaction notes

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