反应详情

The title compound was prepared in 96% yield from 4-(1,1-dioxo-5-methyl-1,2,5-thiadiazolidin-2-yl)aniline hydrochloride using a similar method to that described for Intermediate 1 (step 1); yellow solid; δH (360 MHz, DMSO-d6) 7.15 (2H, d, J=8.9 Hz, Ar--H), 6.92 (2H, d, J=8.9 Hz, Ar--H), 3.74 (2H, t, J=6.4 Hz, --CH2 --), 3.42 (2H, t, J=6.4 Hz, --CH2 --), 2.68 (3H, s, --CH3); m/z (FAB) 243 (M+ +1).